1960 Democratic National Convention in the context of "Henry Cabot Lodge Jr."

The 1960 presidential campaign of John F. Kennedy, then junior United States senator from Massachusetts, was formally launched on January 2, 1960, as Senator Kennedy announced his intention to seek the Democratic Party nomination for the presidency of the United States in the 1960 presidential election.

Kennedy was nominated by the Democratic Party at the national convention on July 15, 1960, and he named Senator Lyndon B. Johnson as his vice-presidential running mate. On November 8, 1960, they defeated incumbent Vice President Richard Nixon and United Nations Ambassador Henry Cabot Lodge Jr. in the general election. Kennedy was sworn in as president on January 20, 1961, and would serve until his assassination on November 22, 1963. His brothers Robert and Ted would both later run for president in 1968 and 1980 respectively, but neither received the presidential nomination.

Presidential elections were held in the United States on November 8, 1960. The Democratic ticket of Senator John F. Kennedy and his running mate, Senate Majority Leader Lyndon B. Johnson, narrowly defeated the Republican ticket of incumbent Vice President Richard Nixon and his running mate, U.N. Ambassador Henry Cabot Lodge Jr. This was the first election in which 50 states participated, marking the first participation of Alaska and Hawaii, and the last in which the District of Columbia did not. It was also the first election in which an incumbent president—in this case, Dwight D. Eisenhower—was ineligible to run for a third term because of the term limits established by the 22nd Amendment.

Nixon faced little opposition in the Republican race to succeed popular incumbent Eisenhower. Kennedy, the junior senator from Massachusetts, established himself as the Democratic frontrunner with his strong performance in the 1960 Democratic primaries, including key victories in Wisconsin and West Virginia over Senator Hubert Humphrey. He defeated Senate Majority Leader Lyndon B. Johnson on the first presidential ballot of the 1960 Democratic National Convention, and asked Johnson to serve as his running mate.

The term New Frontier was used by Democratic presidential candidate John F. Kennedy in his acceptance speech, delivered July 15, to the 1960 Democratic National Convention at the Los Angeles Memorial Coliseum. The phrase became a label for his administration's domestic and foreign programs.

In the words of Robert D. Marcus: "Kennedy entered office with ambitions to eradicate poverty and to raise America's eyes to the stars through the space program."

From March 8 to June 7, 1960, voters and members of the Democratic Party elected delegates to the 1960 Democratic National Convention through a series of caucuses, conventions, and primaries, partly for the purpose of nominating a candidate for President of the United States in the 1960 election. The presidential primaries were inconclusive, as several of the leading contenders did not enter them, but U.S. Senator John F. Kennedy of Massachusetts emerged as the strongest candidate and won the nomination over Lyndon B. Johnson at the convention, held from July 11 to 15 at the Los Angeles Memorial Sports Arena.

Recalling the experience of 1928 Democratic nominee Al Smith (who was Catholic), many wondered if anti-Catholic prejudice would affect Kennedy's chances of winning the nomination and the election in November. To prove his vote-getting ability, Kennedy challenged U.S. senator Hubert Humphrey of Minnesota, a liberal, in the Wisconsin primary. Although Kennedy defeated Humphrey in Wisconsin, his reliance on heavily Catholic areas left many party bosses unconvinced. Kennedy thus faced Humphrey in the heavily Protestant state of West Virginia. Humphrey's campaign was low on money and could not compete with the well-organized, well-financed Kennedy team. Kennedy's siblings combed the state looking for votes, leading Humphrey to complain that he "felt like an independent merchant running against a chain store." On primary day, Kennedy crushed Humphrey with over 60% of the vote, and Humphrey withdrew from the race.