1854 Broad Street cholera outbreak in the context of "1846–1860 cholera pandemic"

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⭐ Core Definition: 1854 Broad Street cholera outbreak

A severe outbreak of cholera occurred in 1854 near Broad Street (now Broadwick Street) and Golden Square in Soho, London, England, during the worldwide 1846–1860 cholera pandemic. The outbreak (also known as Golden Square outbreak), which killed 616 people, is best known for the physician John Snow's study of its causes and his hypothesis that germ-contaminated water was the cause, rather than something in the air called "miasma". This discovery influenced public health and the construction of improved sanitation facilities beginning in the mid-19th century. Later, the term "focus of infection" was used to describe sites, such as the Broad Street pump, where conditions are favourable for transmission of infection. Snow unknowingly took advantage of a natural experiment during his endeavours to identify the cause of cholera transmission.

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1854 Broad Street cholera outbreak in the context of Geospatial analysis

Spatial analysis is any of the formal techniques which study entities using their topological, geometric, or geographic properties, primarily used in urban design. Spatial analysis includes a variety of techniques using different analytic approaches, especially spatial statistics. It may be applied in fields as diverse as astronomy, with its studies of the placement of galaxies in the cosmos, or to chip fabrication engineering, with its use of "place and route" algorithms to build complex wiring structures. In a more restricted sense, spatial analysis is geospatial analysis, the technique applied to structures at the human scale, most notably in the analysis of geographic data. It may also applied to genomics, as in transcriptomics data, but is primarily for spatial data.

Complex issues arise in spatial analysis, many of which are neither clearly defined nor completely resolved, but form the basis for current research. The most fundamental of these is the problem of defining the spatial location of the entities being studied. Classification of the techniques of spatial analysis is difficult because of the large number of different fields of research involved, the different fundamental approaches which can be chosen, and the many forms the data can take.

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1854 Broad Street cholera outbreak in the context of John Snow

John Snow (15 March 1813 – 16 June 1858) was an English physician and a leader in the development of anaesthesia and medical hygiene. He is considered one of the founders of modern epidemiology and early germ theory, in part because of his work in tracing the source of a cholera outbreak in London's Soho, which he identified as a particular public water pump. Snow's findings inspired fundamental changes in the water and waste systems of London, which led to similar changes in other cities, and a significant improvement in general public health around the world.

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1854 Broad Street cholera outbreak in the context of Cluster (epidemiology)

A disease cluster is an unusually large aggregation of a relatively uncommon disease (medical condition) or event within a particular geographical location or period. Recognition of a cluster depends on its size being greater than would be expected by chance. Identification of a suspected disease cluster may initially depend on anecdotal evidence. Epidemiologists and biostatisticians then assess whether the suspected cluster corresponds to an actual increase of disease in the area. Typically, when clusters are recognized, they are reported to public health departments in the local area. If clusters are of sufficient size and importance, they may be re-evaluated as outbreaks.

John Snow's pioneering investigation of the 1854 cholera outbreak in Soho, London, is seen as a classic example of the study of such a cluster.

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1854 Broad Street cholera outbreak in the context of Broadwick Street

Broadwick Street (formerly Broad Street) is a street in Soho, City of Westminster, London. It runs for 0.18 miles (0.29 km) approximately west–east between Marshall Street and Wardour Street, crossing Berwick Street. The street extends across four separate estates, Colman Hedge Close, Little Gelding's, Pawlett's Garden and Pesthouse.

Broad Street was notorious as the centre of an 1854 outbreak of cholera. This outbreak killed a total of 700 people and only twelve escaped. Physician John Snow traced the outbreak to a public water pump on the street, and disabled the pump. Before this time, the disease was widely thought to be caused by air-borne 'miasma'; Snow's findings showed it to be water-borne.

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